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Trequinsin hydrochloride
CAS No. 78416-81-6
Trequinsin hydrochloride ( HL 725 )
产品货号. M15958 CAS No. 78416-81-6
Trequinsin hydrochloride (HL 725) is a potent, cell-permeable, orally active inhibitor of cGMP-inhibited phosphodiesterase (PCE3 IC50=250 pM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥6658 | 有现货 |
|
| 100MG | ￥11016 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Trequinsin hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Trequinsin hydrochloride (HL 725) is a potent, cell-permeable, orally active inhibitor of cGMP-inhibited phosphodiesterase (PCE3 IC50=250 pM).
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产品描述Trequinsin hydrochloride (HL 725) is a potent, cell-permeable, orally active inhibitor of cGMP-inhibited phosphodiesterase (PCE3 IC50=250 pM), inhibits arachidonic acid-induced aggregation of human platelets with IC50 of 50 pM; reduces systemic blood pressure in both normotensive and hypertensive animal models.Hypertension Discontinued
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同义词HL 725
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通路Angiogenesis
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靶点PDE
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受体PDE
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研究领域Cardiovascular Disease
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适应症Hypertension
化学信息
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CAS Number78416-81-6
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分子量441.96
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分子式C24H28ClN3O3
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2C)OC)OC)C.Cl
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化学全称2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lal B, et al. J Med Chem. 1984 Nov;27(11):1470-80.
2. Ruppert D, et al. Life Sci. 1982 Nov 8;31(19):2037-43.
3. Darius H, et al. Br J Pharmacol. 1985 Mar;84(3):735-41.
4. Blaskó G, et al. Thromb Res. 1986 Jul 15;43(2):249-50.
2. Ruppert D, et al. Life Sci. 1982 Nov 8;31(19):2037-43.
3. Darius H, et al. Br J Pharmacol. 1985 Mar;84(3):735-41.
4. Blaskó G, et al. Thromb Res. 1986 Jul 15;43(2):249-50.
产品手册
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